513.221.1100 or 800.325.7787

Office locations

Mayfield Brain & Spine

3825 Edwards Road, Suite 300

Cincinnati, Ohio 45209

Marc P. Orlando, MD

Interventional Pain Management Specialist

Areas of expertise –interventional spinal treatments and therapies, such as transforaminal epidural steroid injections, facet injections, nerve blocks, radiofrequency ablation, spinal cord stimulation; treatment of low back pain, complex regional pain syndrome (CRPS), sacroiliac joint pain, herniated disc, spinal stenosis; nerve block and radiofrequency ablation for hip, knee or sacroiliac joint pain; trigger point and major joint injections


  • Undergraduate: Physical Therapy, Bowling Green State University, 1988
  • Medical School: University of Cincinnati College of Medicine, 1993
  • Residency: Internal Medicine and Physical Medicine and Rehabilitation, University of Cincinnati College of Medicine, 1993-1998


    American Board of Physical Medicine and Rehabilitation


  • Mayfield Brain & Spine, Cincinnati: Interventional Pain Management Specialist, 2014-present
  • Mayfield Spine Surgery Center: Medical Advisory Committee member
  • Nevro: Physician Consultant, 2019-present
  • SI BONE: Physician Consultant, 2017-present
  • Medtronic Neuromodulation: Physician Consultant, 2011-2013
  • Good Samaritan and Bethesda North Hospitals: Staff physician, Physical Medicine and Rehabilitation, 1998-present
  • TriHealth Orthopedic and Spine Institute: Medical Director of Spine Care, 2014-2017
  • Group Health Associates: Physician/Partner, 1998-2014; Director of Musculoskeletal Medicine, 2001-2012; Urgent Care Physician, 1994-1999
  • Mercy Hospital Mt. Airy: Medical Director, Pain Management, 2007-2013
  • Rehab Transitional Care Partners, Cincinnati: CEO/Founder and Medical Director, 2005-2012
  • Medical Associates and Rehabilitation Consultants, Cincinnati: CEO/Founder and Medical Director, 2003-2012
  • Select Hospitals: Medical Director of Neurological Rehabilitation, 2003-2008
  • NOVA Care: Medical Director, Work Hardening Program, 2003-2004
  • UC College of Medicine: Assistant Adjunct Professor, 2001-2004

Primary hospital affiliations*

Mayfield Spine Surgery Center

*Mayfield is affiliated with most major hospitals in Cincinnati and Northern Kentucky

Professional memberships

  • American Medical Association
  • American Academy of Physical Medicine and Rehabilitation
  • Academy of Medicine of Cincinnati
  • International Spinal Interventional Society
  • Ohio State Medical Association
  • North America Neuromodulation Society

Related links

Physician spotlight: Dr. Marc Orlando

Seventeen Mayfield Specialists Named to Regional and National 'Top Doctors' Lists

Nimmie's story: Osteoarthritis

Anisa's story: Chronic pain

YouTube: Dr. Marc Orlando discusses the SI joint - Low Back Pain's Missing Link

Lexi's story: Reflex sympathetic dystrophy - RSD

TriHealth and Mayfield Clinic Announce Collaboration for Community-Based Neurosurgery Services